SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
SLC7A11 is a cell transmembrane protein composing the light chain of system xc<sup>−</sup>, transporting extracellular cystine into cells for cysteine production and GSH biosynthesis. SLC7A11 is a critical gateway for redox homeostasis by maintaining the cellular levels of GSH that count...
| Main Authors: | , |
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| 格式: | Article |
| 語言: | English |
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MDPI AG
2022-12-01
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| 叢編: | Antioxidants |
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| 在線閱讀: | https://www.mdpi.com/2076-3921/11/12/2444 |