Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response

Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response

In a study using both human cells and the African green monkeys, Enchery et al report that the highly pathogenic bat-borne Nipah virus (NiV), inhibits the NF-κB pathway via its nonstructural W protein. They demonstrate that it exerts this effect by causing nuclear accumulation of the cellular scaffo...

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Bibliographic Details
Main Authors: François Enchéry, Claire Dumont, Mathieu Iampietro, Rodolphe Pelissier, Noémie Aurine, Louis-Marie Bloyet, Caroline Carbonnelle, Cyrille Mathieu, Chloé Journo, Denis Gerlier, Branka Horvat
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02797-5

Internet

https://doi.org/10.1038/s42003-021-02797-5

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