Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response
In a study using both human cells and the African green monkeys, Enchery et al report that the highly pathogenic bat-borne Nipah virus (NiV), inhibits the NF-κB pathway via its nonstructural W protein. They demonstrate that it exerts this effect by causing nuclear accumulation of the cellular scaffo...
Main Authors: | François Enchéry, Claire Dumont, Mathieu Iampietro, Rodolphe Pelissier, Noémie Aurine, Louis-Marie Bloyet, Caroline Carbonnelle, Cyrille Mathieu, Chloé Journo, Denis Gerlier, Branka Horvat |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02797-5 |
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