Telophase correction refines division orientation in stratified epithelia

Telophase correction refines division orientation in stratified epithelia

During organogenesis, precise control of spindle orientation balances proliferation and differentiation. In the developing murine epidermis, planar and perpendicular divisions yield symmetric and asymmetric fate outcomes, respectively. Classically, division axis specification involves centrosome mig...

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Bibliographic Details
Main Authors: Kendall J Lough, Kevin M Byrd, Carlos P Descovich, Danielle C Spitzer, Abby J Bergman, Gerard MJ Beaudoin III, Louis F Reichardt, Scott E Williams
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
oriented cell division
spindle orientation
asymmetric cell division
epidermal differentiation
adherens junction
cell-cell adhesion
Online Access:https://elifesciences.org/articles/49249

Internet

https://elifesciences.org/articles/49249

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