GLUT3 Promotes Epithelial–Mesenchymal Transition via TGF-β/JNK/ATF2 Signaling Pathway in Colorectal Cancer Cells

GLUT3 Promotes Epithelial–Mesenchymal Transition via TGF-β/JNK/ATF2 Signaling Pathway in Colorectal Cancer Cells

Glucose transporter (GLUT) 3, a member of the GLUTs family, is involved in cellular glucose utilization and the first step in glycolysis. GLUT3 is highly expressed in colorectal cancer (CRC) and it leads to poor prognosis to CRC patient outcome. However, the molecular mechanisms of GLUT3 on the epit...

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Bibliographic Details
Main Authors: Moon-Young Song, Da-Young Lee, Sun-Mi Yun, Eun-Hee Kim
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
colorectal cancer
glucose transporter 3
epithelial–mesenchymal transition
c-Jun N-terminal kinase
activating transcription factor-2
transforming growth factor-β
Online Access:https://www.mdpi.com/2227-9059/10/8/1837

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https://www.mdpi.com/2227-9059/10/8/1837

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