Reconstitution of multifunctional CD56lowCD16low natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation

Reconstitution of multifunctional CD56lowCD16low natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation

We recently described the CD56lowCD16low subset of Natural Killer (NK) cells that both mediate cytotoxic activity and produce IFNγ, being more abundant in bone marrow (BM) than in peripheral blood (PB) of pediatric normal subjects. Given the multifunctional properties of this subset, we examined its...

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Bibliographic Details
Main Authors: Helena Stabile, Paolo Nisti, Giovanna Peruzzi, Cinzia Fionda, Daria Pagliara, Pomonia Letizia Brescia, Pietro Merli, Franco Locatelli, Angela Santoni, Angela Gismondi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:OncoImmunology
Subjects:
natural killer cell subsets
haematopoietic stem cell transplantation
haematological malignancies
phenotype
cytokine production
cytotoxicity
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1342024

Internet

http://dx.doi.org/10.1080/2162402X.2017.1342024

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