Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature

Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prev...

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Principais autores: Seyedeh Maryam Sharafi, Raheleh Rafiei Sefiddashti, Behnam Sanei, Morteza Yousefi, Hossein Yousofi Darani
Formato: Artigo
Idioma:English
Publicado em: Wolters Kluwer Medknow Publications 2017-01-01
coleção:Journal of Research in Medical Sciences
Assuntos:
Acesso em linha:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=Sharafi
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author Seyedeh Maryam Sharafi
Raheleh Rafiei Sefiddashti
Behnam Sanei
Morteza Yousefi
Hossein Yousofi Darani
author_facet Seyedeh Maryam Sharafi
Raheleh Rafiei Sefiddashti
Behnam Sanei
Morteza Yousefi
Hossein Yousofi Darani
author_sort Seyedeh Maryam Sharafi
collection DOAJ
description Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prevent this problem scolicidal agent such as hypertonic salt are used to kill the protoscolices that may disseminate into the patient's tissues during surgery. However, they may have some unacceptable side effects. To find scolicidal agents with high efficacy, the effect of different compounds on protoscolices of hydatid cyst in vitro has been reviewed. Using PubMed, Scopus, Google Scholar, and SID databases articles about scolicidal effects of different agents on protoscolices of hydatid cyst in vitro were collected. Foeniculum vulgare after 5 min, metalonic extracts of Allium sativum and hypertonic saline after 10 min, and warm water after 2 min kill all alive protoscolices. The above agents that in minimum time and minimum concentration have 100% scolicidal activity, could be good candidates for further investigations.
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spelling doaj.art-dc7e77f2b1a0498eba4627aca677a39c2022-12-21T22:26:32ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362017-01-01221929210.4103/jrms.JRMS_1030_16Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literatureSeyedeh Maryam SharafiRaheleh Rafiei SefiddashtiBehnam SaneiMorteza YousefiHossein Yousofi DaraniHydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prevent this problem scolicidal agent such as hypertonic salt are used to kill the protoscolices that may disseminate into the patient's tissues during surgery. However, they may have some unacceptable side effects. To find scolicidal agents with high efficacy, the effect of different compounds on protoscolices of hydatid cyst in vitro has been reviewed. Using PubMed, Scopus, Google Scholar, and SID databases articles about scolicidal effects of different agents on protoscolices of hydatid cyst in vitro were collected. Foeniculum vulgare after 5 min, metalonic extracts of Allium sativum and hypertonic saline after 10 min, and warm water after 2 min kill all alive protoscolices. The above agents that in minimum time and minimum concentration have 100% scolicidal activity, could be good candidates for further investigations.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=SharafiHydatid cystprotoscolicesscolicidal agentssurgerysurgery
spellingShingle Seyedeh Maryam Sharafi
Raheleh Rafiei Sefiddashti
Behnam Sanei
Morteza Yousefi
Hossein Yousofi Darani
Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
Journal of Research in Medical Sciences
Hydatid cyst
protoscolices
scolicidal agents
surgery
surgery
title Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
title_full Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
title_fullStr Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
title_full_unstemmed Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
title_short Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
title_sort scolicidal agents for protoscolices of echinococcus granulosus hydatid cyst review of literature
topic Hydatid cyst
protoscolices
scolicidal agents
surgery
surgery
url http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=Sharafi
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