Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prev...
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Formato: | Artigo |
Idioma: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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coleção: | Journal of Research in Medical Sciences |
Assuntos: | |
Acesso em linha: | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=Sharafi |
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author | Seyedeh Maryam Sharafi Raheleh Rafiei Sefiddashti Behnam Sanei Morteza Yousefi Hossein Yousofi Darani |
author_facet | Seyedeh Maryam Sharafi Raheleh Rafiei Sefiddashti Behnam Sanei Morteza Yousefi Hossein Yousofi Darani |
author_sort | Seyedeh Maryam Sharafi |
collection | DOAJ |
description | Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prevent this problem scolicidal agent such as hypertonic salt are used to kill the protoscolices that may disseminate into the patient's tissues during surgery. However, they may have some unacceptable side effects. To find scolicidal agents with high efficacy, the effect of different compounds on protoscolices of hydatid cyst in vitro has been reviewed. Using PubMed, Scopus, Google Scholar, and SID databases articles about scolicidal effects of different agents on protoscolices of hydatid cyst in vitro were collected. Foeniculum vulgare after 5 min, metalonic extracts of Allium sativum and hypertonic saline after 10 min, and warm water after 2 min kill all alive protoscolices. The above agents that in minimum time and minimum concentration have 100% scolicidal activity, could be good candidates for further investigations. |
first_indexed | 2024-12-16T15:24:52Z |
format | Article |
id | doaj.art-dc7e77f2b1a0498eba4627aca677a39c |
institution | Directory Open Access Journal |
issn | 1735-1995 1735-7136 |
language | English |
last_indexed | 2024-12-16T15:24:52Z |
publishDate | 2017-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Research in Medical Sciences |
spelling | doaj.art-dc7e77f2b1a0498eba4627aca677a39c2022-12-21T22:26:32ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362017-01-01221929210.4103/jrms.JRMS_1030_16Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literatureSeyedeh Maryam SharafiRaheleh Rafiei SefiddashtiBehnam SaneiMorteza YousefiHossein Yousofi DaraniHydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prevent this problem scolicidal agent such as hypertonic salt are used to kill the protoscolices that may disseminate into the patient's tissues during surgery. However, they may have some unacceptable side effects. To find scolicidal agents with high efficacy, the effect of different compounds on protoscolices of hydatid cyst in vitro has been reviewed. Using PubMed, Scopus, Google Scholar, and SID databases articles about scolicidal effects of different agents on protoscolices of hydatid cyst in vitro were collected. Foeniculum vulgare after 5 min, metalonic extracts of Allium sativum and hypertonic saline after 10 min, and warm water after 2 min kill all alive protoscolices. The above agents that in minimum time and minimum concentration have 100% scolicidal activity, could be good candidates for further investigations.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=SharafiHydatid cystprotoscolicesscolicidal agentssurgerysurgery |
spellingShingle | Seyedeh Maryam Sharafi Raheleh Rafiei Sefiddashti Behnam Sanei Morteza Yousefi Hossein Yousofi Darani Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature Journal of Research in Medical Sciences Hydatid cyst protoscolices scolicidal agents surgery surgery |
title | Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature |
title_full | Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature |
title_fullStr | Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature |
title_full_unstemmed | Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature |
title_short | Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature |
title_sort | scolicidal agents for protoscolices of echinococcus granulosus hydatid cyst review of literature |
topic | Hydatid cyst protoscolices scolicidal agents surgery surgery |
url | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=92;epage=92;aulast=Sharafi |
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