Cytokine Release Syndrome in Cancer Patients Receiving Immune Checkpoint Inhibitors: A Case Series of 25 Patients and Review of the Literature

Cytokine release syndrome (CRS) is a phenomenon of immune hyperactivation described in the setting of immunotherapy. Unlike other immune-related adverse events, CRS triggered by immune checkpoint inhibitors (ICIs) is not well described. The clinical characteristics and course of 25 patients with ICI...

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Main Authors: Sen Hee Tay, Michelle Min Xuan Toh, Yee Liang Thian, Balamurugan A. Vellayappan, Anna-Marie Fairhurst, Yiong Huak Chan, Folefac Aminkeng, Lavina D. Bharwani, Yiqing Huang, Anselm Mak, Alvin Seng Cheong Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.807050/full