Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice

Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice

Acetaminophen (APAP) is one of the most commonly used analgesic and anti-pyretic drugs, and APAP intoxication is one of the main reasons for liver transplantation following liver failure in the Western world. While APAP poisoning ultimately leads to liver necrosis, various programmed cell death moda...

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Bibliographic Details
Main Authors: Samara Naim, Yuniel Fernandez-Marrero, Simone de Brot, Daniel Bachmann, Thomas Kaufmann
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
BOK
BCL-2 family
acetaminophen
ER stress
UPR
apoptosis
Online Access:https://www.mdpi.com/1422-0067/22/6/3281

Internet

https://www.mdpi.com/1422-0067/22/6/3281

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