Why is motilin active in some studies with mice, rats, and guinea pigs, but not in others? Implications for functional variability among rodents
Abstract The gastrointestinal (GI) hormone motilin helps control human stomach movements during hunger and promotes hunger. Although widely present among mammals, it is generally accepted that in rodents the genes for motilin and/or its receptor have undergone pseudonymization, so exogenous motilin...
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Format: | Article |
Language: | English |
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Wiley
2022-04-01
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Series: | Pharmacology Research & Perspectives |
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Online Access: | https://doi.org/10.1002/prp2.900 |