SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence

SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence

Abstract Thoracic aortic aneurysms (TAAs) develop asymptomatically and are characterized by dilatation of the aorta. This is considered a life-threating vascular disease due to the risk of aortic rupture and without effective treatments. The current understanding of the pathogenesis of TAA is still...

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Bibliographic Details
Main Authors: Yang-Nan Ding, Ting-Ting Wang, Shuang-Jie Lv, Xiaoqiang Tang, Zi-Yu Wei, Fang Yao, Han-Shi Xu, Yi-Nan Chen, Xiao-Man Wang, Hui-Yu Wang, He-Ping Wang, Zhu-Qin Zhang, Xiang Zhao, De-Long Hao, Li-Hong Sun, Zhou Zhou, Li Wang, Hou-Zao Chen, De-Pei Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01456-x

Internet

https://doi.org/10.1038/s41392-023-01456-x

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