Metformin Suppresses Ovarian Cancer Growth and Metastasis with Enhancement of Cisplatin Cytotoxicity In Vivo

Ovarian cancer is the most lethal gynecologic cancer in women. Its high mortality rate (68%) reflects the fact that 75% of patients have extensive (>stage III) disease at diagnosis and also the limited efficacy of currently available therapies. Consequently, there is clearly a great need to devel...

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Bibliographic Details
Main Authors: Ramandeep Rattan, Rondell P. Graham, Jacie L. Maguire, Shailendra Giri, Viji Shridhar
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800667