Effects of Insulin-Like Growth Factor-I on the Expression of Atrogin-1/MAFbx in Chick Myotube Cultures

Effects of Insulin-Like Growth Factor-I on the Expression of Atrogin-1/MAFbx in Chick Myotube Cultures

The expression of atrogin-1/MAFbx, a muscle-specific E3 ubiquitin ligase, is increased in catabolic conditions that result in muscle atrophy. The expression of atrogin-1/MAFbx mRNA is also decreased by the insulin-like growth factor-I (IGF-I) in mammalian skeletal muscle cell cultures. This study...

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Bibliographic Details
Main Authors: Kazuki Nakashima, Aiko Ishida, Saki Shimamoto, Daichi Ijiri, Akira Ohtsuka
Format: Article
Language:English
Published: Japan Poultry Science Association 2017-07-01
Series:The Journal of Poultry Science
Subjects:
akt
atrogin-1/mafbx
chick myotubes
foxo1
igf-i
Online Access:https://www.jstage.jst.go.jp/article/jpsa/54/3/54_0160141/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jpsa/54/3/54_0160141/_pdf/-char/en

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