Immunomodulation as a Protective Strategy in Chronic Otitis Media

IntroductionMajor features of the pathogenesis in otitis media, the most common disease in childhood, include hyperplasia of the middle ear mucosa and infiltration by leukocytes, both of which typically resolve upon bacterial clearance via apoptosis. Activation of innate immune receptors during the...

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Bibliographic Details
Main Authors: Anke Leichtle, Arwa Kurabi, David Leffers, Markus Därr, Clara Sophia Draf, Allen Frederic Ryan, Karl-Ludwig Bruchhage
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.826192/full