In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation

In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation

Abstract Direct exposure to the fungal species Alternaria alternata is a major risk factor for the development of asthma, allergic rhinitis, and inflammation. As of November 23rd 2020, the NCBI protein database showed 11,227 proteins from A. alternata genome as hypothetical proteins (HPs). Allergens...

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Bibliographic Details
Main Authors: Rajamanikandan Sundararaj, Amala Mathimaran, Dhamodharan Prabhu, Balajee Ramachandran, Jeyakanthan Jeyaraman, Saravanan Muthupandian, Tsehaye Asmelash
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Alternaria alternata
AlgPred
SDAP
Structure–function relationship and drug discovery
Online Access:https://doi.org/10.1038/s41598-024-55463-1

Internet

https://doi.org/10.1038/s41598-024-55463-1

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