A Model for Predicting Cation Selectivity and Permeability in AMPA and NMDA Receptors Based on Receptor Subunit Composition

A Model for Predicting Cation Selectivity and Permeability in AMPA and NMDA Receptors Based on Receptor Subunit Composition

Glutamatergic AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) and NMDA (N-methyl-D-aspartate) receptors are implicated in diverse functions ranging from synaptic plasticity to cell death. They are heterotetrameric proteins whose subunits are derived from multiple distinct gene families....

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Bibliographic Details
Main Authors: Sampath Kumar, Sanjay S. Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
ion selectivity
ion permeability
AMPA receptors
NMDA receptors
subunit composition
charge permeability equation
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.779759/full

Internet

https://www.frontiersin.org/articles/10.3389/fnsyn.2021.779759/full

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