Torque teno mini virus driven childhood acute promyelocytic leukemia: The third case report and sequence analysis

Torque teno mini virus driven childhood acute promyelocytic leukemia: The third case report and sequence analysis

In this manuscript, we report torque teno mini virus (TTMV) as a cause of acute promyelocytic leukemia (APL) lacking PML::RARA in a 3-year-old boy. Astolfi et al. firstly identified partial integration of the TTMV genome into RARA intron 2, which resulted in in-frame TTMV::RARA fusion in two APL-lik...

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Bibliographic Details
Main Authors: Xue Chen, Fang Wang, Xiaosu Zhou, Yang Zhang, Panxiang Cao, Xiaoli Ma, Lili Yuan, Jiancheng Fang, Mingyue Liu, Ming Liu, Jiaqi Chen, Qihui Chen, Ping Wu, Yue Lu, Xiujuan Ma, Hongxing Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
acute promyelocytic leukemia
torque teno mini virus
RARA
TTMV::RARA
whole-transcriptome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1074913/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1074913/full

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