Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction

Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and polarity. Members of the Rho-related family of small GTPases and their interacting proteins play multiple roles in regulating epithelial morphog...

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Bibliographic Details
Main Authors: David A. F. Loebel, Timothy F. Plageman, Theresa L. Tang, Vanessa J. Jones, Maria Muccioli, Patrick P. L. Tam
Format: Article
Language:English
Published: The Company of Biologists 2016-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/2/130