Systemic depletion of WWP1 improves insulin sensitivity and lowers triglyceride content in the liver of obese mice

Systemic depletion of WWP1 improves insulin sensitivity and lowers triglyceride content in the liver of obese mice

Obesity is a metabolic disorder associated with many diseases. WW domain‐containing E3 ubiquitin protein ligase 1 (WWP1) is a HECT‐type E3 ubiquitin ligase involved in several diseases. Recently, we found that the level of WWP1 is increased in white adipose tissue in a mouse model of obesity and tha...

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Bibliographic Details
Main Authors: Yuka Nozaki, Masaki Kobayashi, Hiroki Wakasawa, Shunsuke Hoshino, Fumika Suwa, Yuko Ose, Ryoma Tagawa, Yoshikazu Higami
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:FEBS Open Bio
Subjects:
adipose tissue
hepatic steatosis
obesity
WWP1
Online Access:https://doi.org/10.1002/2211-5463.13610

Internet

https://doi.org/10.1002/2211-5463.13610

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