MCI-frcnn: A deep learning method for topological micro-domain boundary detection

MCI-frcnn: A deep learning method for topological micro-domain boundary detection

Chromatin structural domains, or topologically associated domains (TADs), are a general organizing principle in chromatin biology. RNA polymerase II (RNAPII) mediates multiple chromatin interactive loops, tethering together as RNAPII-associated chromatin interaction domains (RAIDs) to offer a framew...

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Bibliographic Details
Main Authors: Simon Zhongyuan Tian, Pengfei Yin, Kai Jing, Yang Yang, Yewen Xu, Guangyu Huang, Duo Ning, Melissa J. Fullwood, Meizhen Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
deep learning
topological micro-domain
faster R-CNN algorithm
3D genome organization
domain boundary
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1050769/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1050769/full

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