Synthesis and characterization of thiolated hexanoyl glycol chitosan as a mucoadhesive thermogelling polymer

Synthesis and characterization of thiolated hexanoyl glycol chitosan as a mucoadhesive thermogelling polymer

Abstract Background Mucoadhesive polymers, which may increase the contact time between the polymer and the tissue, have been widely investigated for pharmaceutical formulations. In this study, we developed a new polysaccharide-based mucoadhesive polymer with thermogelling properties. Methods Hexanoy...

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Bibliographic Details
Main Authors: Ik Sung Cho, Hye Min Oh, Myeong Ok Cho, Bo Seul Jang, Jung-Kyo Cho, Kyoung Hwan Park, Sun-Woong Kang, Kang Moo Huh
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2018-09-01
Series:Biomaterials Research
Subjects:
Hexanoyl glycol chitosan
Chemical modification
Mucoadhesive polymer
Rheological measurements
Thermogelling property
Thiolation
Online Access:http://link.springer.com/article/10.1186/s40824-018-0137-7

Internet

http://link.springer.com/article/10.1186/s40824-018-0137-7

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