Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling

The mammary epithelium comprises two cell lineages but the heterogeneity amongst these during development is unclear. Here, the authors report single-cell RNA sequencing of the mouse mammary epithelium at four developmental stages, revealing diversity in both compartments and a transcriptional shift...

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Bibliographic Details
Main Authors: Bhupinder Pal, Yunshun Chen, François Vaillant, Paul Jamieson, Lavinia Gordon, Anne C. Rios, Stephen Wilcox, Naiyang Fu, Kevin He Liu, Felicity C. Jackling, Melissa J. Davis, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01560-x