Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection

Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection

Abstract Background Visceral leishmaniasis is a severe and potentially fatal disease caused by protozoa of the genus Leishmania, transmitted by phlebotomine sandflies. In Europe and the Mediterranean region, L. infantum is the commonest agent of visceral leishmaniasis, causing a wide spectrum of cli...

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Main Authors: Filipe Marques, Sílvia Vale-Costa, Tânia Cruz, Joana Moreira Marques, Tânia Silva, João Vilares Neves, Sofia Cortes, Ana Fernandes, Eduardo Rocha, Rui Appelberg, Pedro Rodrigues, Ana M. Tomás, Maria Salomé Gomes
Format: Article
Language:English
Published: BMC 2015-12-01
Series:Parasites & Vectors
Subjects:
Nitric Oxide
Visceral Leishmaniasis
Leishmaniasis
Arginase
Granuloma Formation
Online Access:https://doi.org/10.1186/s13071-015-1259-6

Internet

https://doi.org/10.1186/s13071-015-1259-6

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