RNA m6A Modification Plays a Key Role in Maintaining Stem Cell Function in Normal and Malignant Hematopoiesis

RNA m6A Modification Plays a Key Role in Maintaining Stem Cell Function in Normal and Malignant Hematopoiesis

N6-methyladenosine (m6A) is a commonly modification of mammalian mRNAs and plays key roles in various cellular processes. Emerging evidence reveals the importance of RNA m6A modification in maintaining stem cell function in normal hematopoiesis and leukemogenesis. In this review, we first briefly su...

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Bibliographic Details
Main Authors: Peipei Wang, Mengdie Feng, Guoqiang Han, Rong Yin, Yashu Li, Shuxin Yao, Pengbo Lu, Yuhua Wang, Haojian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RNA m6A
hematopoietic stem cells
leukemia stem cells
hematopoiesis
myeloid leukemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.710964/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.710964/full

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