Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR

Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR

Abstract Background Triple negative breast cancer (TNBC) is a major subtype of breast cancer, with limited therapeutic drugs in clinical. Epidermal growth factor receptor (EGFR) is reported to be overexpressed in various TNBC cells. Cantharidin is an effective ingredient in many clinical traditional...

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Bibliographic Details
Main Authors: Tianfeng Yang, Runze Yu, Cheng Cheng, Jian Huo, Zhengyan Gong, Hanbing Cao, Yu Hu, Bingling Dai, Yanmin Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
TNBC
Cantharidin
EGFR
miR-607
Apoptosis
Online Access:https://doi.org/10.1186/s12967-023-04483-y

Internet

https://doi.org/10.1186/s12967-023-04483-y

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