Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system

Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system

Neural stem cells (NSCs) are considered to be valuable candidates for delivering a variety of anti‐cancer agents, including oncolytic viruses, to brain tumors. However, owing to the previously reported tumorigenic potential of NSC cell lines after intranasal administration (INA), here we identified...

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Bibliographic Details
Main Authors: Ali El‐Ayoubi, Arsen Arakelyan, Moritz Klawitter, Luisa Merk, Siras Hakobyan, Irene Gonzalez‐Menendez, Leticia Quintanilla Fend, Per Sonne Holm, Wolfgang Mikulits, Matthias Schwab, Lusine Danielyan, Ulrike Naumann
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Molecular Oncology
Subjects:
hepatic stellate cells
intranasal delivery
optimized shuttle cells
Online Access:https://doi.org/10.1002/1878-0261.13569

Internet

https://doi.org/10.1002/1878-0261.13569

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