Frequent birth-and-death events throughout perforin-1 evolution

Frequent birth-and-death events throughout perforin-1 evolution

Abstract Background Through its ability to open pores in cell membranes, perforin-1 plays a key role in the immune system. Consistent with this role, the gene encoding perforin shows hallmarks of complex evolutionary events, including amplification and pseudogenization, in multiple species. A large...

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Bibliographic Details
Main Authors: Miguel Araujo-Voces, Víctor Quesada
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Evolutionary Biology
Subjects:
Perforin-1
Assisted annotation
Immune
Birth-and-death
Tandem duplication
Online Access:http://link.springer.com/article/10.1186/s12862-020-01698-1

Internet

http://link.springer.com/article/10.1186/s12862-020-01698-1

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