Regulation and migratory role of P-selectin ligands during intestinal inflammation.

Dendritic cells from mesenteric lymph nodes (MLN) can convert retinal to retinoic acid (RA), which promotes induction of the gut-specific homing receptor α4β7. In contrast, priming within peripheral lymph nodes leads to upregulation of E- and P-selectin ligands (E- and P-lig). Apart from its α4β7 pr...

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Bibliographic Details
Main Authors: Ute Hoffmann, Matthias Pink, Uta Lauer, Markus M Heimesaat, Caroline Winsauer, Andrei Kruglov, Kerstin Schlawe, Claudia Leichsenring, Oliver Liesenfeld, Alf Hamann, Uta Syrbe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632518?pdf=render