Perturbation of EGF-induced MAP kinase activation by TGF-ß1
TGF-ß1 regulates both cellular growth and phenotypic plasticity important for maintaining a growth advantage and increased invasiveness in progressively malignant cells. Recent studies indicate that TGF-ß-1 stimulates the conversion of epitheliod to fibroblastoid phenotype which presumably leads to...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
1999-07-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700004 |