Amino acid substitution of the membrane-proximal external region alter neutralization sensitivity in a chronic HIV-1 clade B infected patient

Amino acid substitution of the membrane-proximal external region alter neutralization sensitivity in a chronic HIV-1 clade B infected patient

The membrane-proximal external region (MPER) represents a highly conserved region of the Human Immunodeficiency Virus (HIV) envelope glycoprotein (env) targeted by several broadly neutralizing antibodies (bnAbs). In this study, we employed single genome amplification to amplify 34 full-length env se...

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Bibliographic Details
Main Authors: Yuyu Fu, Shuhui Wang, Yanling Hao, Dan Li, Li Ren, Zheng Wang, Ran Chen, Wenqi Tang, Xiuli Shen, Wanqi Ni, Yutao Shi, Meiling Zhu, Yiming Shao, Ying Liu
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Virus Research
Subjects:
HIV-1
MPER
Mutation
Neutralization sensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224000704

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http://www.sciencedirect.com/science/article/pii/S0168170224000704

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