Altered Spontaneous Brain Activity in Subjects With Different Cognitive States of Biologically Defined Alzheimer's Disease: A Surface-Based Functional Brain Imaging Study

Altered Spontaneous Brain Activity in Subjects With Different Cognitive States of Biologically Defined Alzheimer's Disease: A Surface-Based Functional Brain Imaging Study

Background: Before the apparent cognitive decline, subjects on the course of Alzheimer's disease (AD) can have significantly altered spontaneous brain activity, which could be potentially used for early diagnosis. As previous studies investigating local brain activity may suffer from the proble...

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Bibliographic Details
Main Authors: Zili Zhu, Qingze Zeng, Linghan Kong, Xiao Luo, Kaicheng Li, Xiaopei Xu, Minming Zhang, Peiyu Huang, Yunjun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
A/T/N system
resting-state functional magnetic resonance imaging
amplitude of low frequency fluctuation
spontaneous brain activity
surface-based analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.683783/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2021.683783/full

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