Protein Phosphatase 4 Is Required for Centrobin Function in DNA Damage Repair

Protein Phosphatase 4 Is Required for Centrobin Function in DNA Damage Repair

Genome stability in human cells relies on the efficient repair of double-stranded DNA breaks, which is mainly achieved by homologous recombination (HR). Among the regulators of various cellular functions, Protein phosphatase 4 (PP4) plays a pivotal role in coordinating cellular response to DNA damag...

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Bibliographic Details
Main Authors: Zsuzsánna Réthi-Nagy, Edit Ábrahám, Rita Sinka, Szilvia Juhász, Zoltán Lipinszki
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
protein phosphatase 4
Centrobin
DNA damage response
homologous recombination repair
arms-closed chromosome morphology
DNA double-stranded break
Online Access:https://www.mdpi.com/2073-4409/12/18/2219

Internet

https://www.mdpi.com/2073-4409/12/18/2219

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