A targeted controlled force injection of genetic material in vivo

A general limitation in gene delivery is the cellular uptake in lager animals including humans. Several approaches have been tested including liposomes, micro-needles, in vivo electro-transfer, ballistic delivery, and needle-free delivery. All these techniques have individual limitations. One approa...

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Bibliographic Details
Main Authors: Gustaf Ahlén, Lars Frelin, Fredrik Höolmstrm, Grant Smetham, Steve Augustyn, Matti Sällberg
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116301577