Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma

In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this mutation grows, so too does the number of mutation subtypes reported in th...

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Bibliographic Details
Main Authors: Victor M Lu, Kerrie L McDonald
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:CNS Oncology
Subjects:
Online Access:https://www.futuremedicine.com/doi/10.2217/cns-2017-0019