Function and mechanism of histone β-hydroxybutyrylation in health and disease

Function and mechanism of histone β-hydroxybutyrylation in health and disease

Histone post-translational modifications (HPTMs) are essential epigenetic mechanisms that affect chromatin-associated nuclear processes without altering the DNA sequence. With the application of mass spectrometry-based proteomics, novel histone lysine acylation, such as propionylation, butyrylation,...

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Bibliographic Details
Main Authors: Tingting Zhou, Xi Cheng, Yanqiu He, Yumei Xie, Fangyuan Xu, Yong Xu, Wei Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
β-hydroxybutyrylation
histone post-translational modifications
epigenetics
gene regulation
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.981285/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.981285/full

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