Bispecific BCMA-CD3 Antibodies Block Multiple Myeloma Tumor Growth

BCMA antigen is overexpressed in multiple myeloma cells and has been shown to be a promising target for novel cellular and antibody therapeutics. The humanized BCMA (clone 4C8A) antibody that effectively targeted multiple myeloma in a CAR (chimeric antigen receptor) format was used for designing sev...

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Bibliographic Details
Main Authors: Lijun Wu, Yanwei Huang, John Sienkiewicz, Jinying Sun, Liselle Guiang, Feng Li, Liming Yang, Vita Golubovskaya
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/10/2518