Single or Divided Administration of Cisplatin Can Induce Inflammation and Oxidative Stress in Male Sprague-Dawley Rats

BACKGROUND: Cisplatin is one of the most potent chemotherapy drugs to treat various types of cancer, however the use of cisplatin has some the adverse effect, such as the increase of oxidative stress and inflammation by malondialdehyde (MDA) and nuclear factor kappa B (NF-kB) activation. Since the d...

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Bibliographic Details
Main Authors: Brigitte Rina Aninda Sidharta, Bambang Purwanto, Brian Wasita, Vitri Widyaningsih, Soetrisno Soetrisno
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2022-06-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/1745