Promoter hypermethylation analysis of host genes in cervical intraepithelial neoplasia and cervical cancers on histological cervical specimens

Promoter hypermethylation analysis of host genes in cervical intraepithelial neoplasia and cervical cancers on histological cervical specimens

Abstract Background DNA methylation is an essential factor in the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer. The aim was to investigate the diagnostic value provided by methylation biomarkers of six tumor suppressor genes (ASTN1, DLX1, ITGA4, RXFP3, SOX17 and ZNF671)...

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Bibliographic Details
Main Authors: Liye Shi, Xue Yang, Ling He, Chunying Zheng, Zhen Ren, Juweria Abdisamad Warsame, Suye Suye, Lei Yan, Haiyi Cai, Xiao Xiao, Chun Fu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
Cervical cancer
Cervical intraepithelial neoplasia
DNA methylation
GynTect® assay
High-risk human papillomavirus
Online Access:https://doi.org/10.1186/s12885-023-10628-5

Internet

https://doi.org/10.1186/s12885-023-10628-5

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