The role of melatonin in amyloid beta-induced inflammation mediated by inflammasome signaling in neuronal cell lines

Abstract Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. In addition to amyloid beta (Aβ) and tau, neuroinflammation is a crucial element in the etiology of this disease. However, the relevance of inflammasome-induced pyroptosis to AD is unknown. We aimed to clarify w...

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Bibliographic Details
Main Authors: Chutikorn Nopparat, Anuttree Boontor, Suchanoot Kutpruek, Piyarat Govitrapong
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45220-1