Encapsulated Brucella ovis Lacking a Putative ATP-Binding Cassette Transporter (ΔabcBA) Protects against Wild Type Brucella ovis in Rams.

Encapsulated Brucella ovis Lacking a Putative ATP-Binding Cassette Transporter (ΔabcBA) Protects against Wild Type Brucella ovis in Rams.

This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against experimental challenge with wild type B. ovis in rams. Rams were subcutaneously immunized with B. ovis ΔabcBA encapsulated with sterile alginate or with the non encapsulated vaccine strain. Serum, urine,...

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Bibliographic Details
Main Authors: Ana Patrícia C Silva, Auricélio A Macêdo, Luciana F Costa, Cláudia E Rocha, Luize N N Garcia, Jade R D Farias, Priscilla P R Gomes, Gustavo C Teixeira, Kessler W J Fonseca, Andréa R F Maia, Gabriela G Neves, Everton L Romão, Teane M A Silva, Juliana P S Mol, Renata M Oliveira, Márcio S S Araújo, Ernane F Nascimento, Olindo A Martins-Filho, Humberto M Brandão, Tatiane A Paixão, Renato L Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0136865

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https://doi.org/10.1371/journal.pone.0136865

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