The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor

The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor

Syndecan-1 (Sdc-1) upregulation is associated with poor prognosis in breast cancer. Sdc-1 knockdown results in reduced angiogenesis and the dysregulation of tissue factor (TF) pathway constituents. Here, we evaluate the regulatory mechanisms and functional consequences of the Sdc-1/TF-axis using Sdc...

Full description

Bibliographic Details
Main Authors: Nourhan Hassan, Nico Bückreiß, Janes Efing, Marie Schulz-Fincke, Philipp König, Burkhard Greve, Gerd Bendas, Martin Götte
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
apoptosis
breast cancer
cell cycle
cell motility
heparan sulfate
platelets
Online Access:https://www.mdpi.com/2073-4409/12/6/910

Internet

https://www.mdpi.com/2073-4409/12/6/910

Similar Items