Influence of solvent mixtures on HPMCAS-celecoxib microparticles prepared by electrospraying
Hypromellose acetate succinate (HPMCAS) microparticles containing the poorly-water soluble drug celecoxib (CEL) were prepared by electrospraying intended for oral drug delivery. Various solvent mixtures with different solubility for CEL and HPMCAS were used to induce changes in the polymer structura...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Asian Journal of Pharmaceutical Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1818087617306487 |