The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin.

The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin.

Cell to cell adhesion is mediated by adhesion molecules present on the cell surface. Downregulation of molecules that form the adhesion complex is a characteristic of metastatic cancer cells. Downregulation of the N-myc down regulated gene1 (NDRG1) increases prostate and breast metastasis. The exact...

Full description

Bibliographic Details
Main Authors: Sushant K Kachhap, Dennis Faith, David Z Qian, Shabana Shabbeer, Nathan L Galloway, Roberto Pili, Samuel R Denmeade, Angelo M DeMarzo, Michael A Carducci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1952073?pdf=render

Internet

http://europepmc.org/articles/PMC1952073?pdf=render

Similar Items