Feedback control of pluripotency in embryonic stem cells: Signaling, transcription and epigenetics

Embryonic stem cells (ESCs) can proliferate and self-renew, maintaining their pluripotency status in vitro for a long period of time. Pluripotent states of ESCs in vitro are supported by a network of signaling, transcriptional and epigenetic regulatory interactions known as the pluripotency gene reg...

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Bibliographic Details
Main Authors: Dmitri Papatsenko, Avinash Waghray, Ihor R. Lemischka
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118300564