Feedback control of pluripotency in embryonic stem cells: Signaling, transcription and epigenetics
Embryonic stem cells (ESCs) can proliferate and self-renew, maintaining their pluripotency status in vitro for a long period of time. Pluripotent states of ESCs in vitro are supported by a network of signaling, transcriptional and epigenetic regulatory interactions known as the pluripotency gene reg...
Main Authors: | Dmitri Papatsenko, Avinash Waghray, Ihor R. Lemischka |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-05-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506118300564 |
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