Wild-Type AmpC Beta-Lactamase-Producing <i>Enterobacterales</i> Are a Risk Factor for Empirical Treatment Failure in Patients with Bloodstream Infection

Wild-Type AmpC Beta-Lactamase-Producing <i>Enterobacterales</i> Are a Risk Factor for Empirical Treatment Failure in Patients with Bloodstream Infection

<b>Introduction:</b> Beta-lactamases are frequently prescribed for Gram-negative bloodstream infections (BSIs). However, chromosomally encoded AmpC-producing <i>Enterobacterales</i> (AE) could overproduce beta-lactamases when exposed to third-generation cephalosporins (3GCs),...

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Bibliographic Details
Main Authors: Matteo Vassallo, Roxane Fabre, Laurene Lotte, Sabrina Manni, Christian Pradier
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Diseases
Subjects:
AmpC-producing <i>Enterobacterales</i>
bloodstream infection
third-generation cephalosporins
treatment failure
Online Access:https://www.mdpi.com/2079-9721/12/3/52

Internet

https://www.mdpi.com/2079-9721/12/3/52

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