The Effect of Polyphenolic Composition BP-C3 on the Efficacy and Hematological Toxicity of Cyclophosphamide in the Chemotherapy of Mice Bearing Soft Tissue Sarcomas Induced by Benzo[a]pyrene

The Effect of Polyphenolic Composition BP-C3 on the Efficacy and Hematological Toxicity of Cyclophosphamide in the Chemotherapy of Mice Bearing Soft Tissue Sarcomas Induced by Benzo[a]pyrene

This study aimed to evaluate the effect of lignin-derived polyphenolic composition BP-C3 on the efficacy and hematological toxicity of cyclophosphamide (CPA). Male and female Swiss-H derived mice bearing benzo[a]pyrene-induced soft tissue sarcomas were treated with CPA 300 mg/kg, BP-C3 75 mg/kg, or...

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Main Authors: Andrey V. Panchenko MD, PhD, Elena I. Fedoros PhD, Sergey E. Pigarev, Mikhail A. Maydin, Ekaterina A. Gubareva, Galina S. Kireeva PhD, Margarita L. Tyndyk PhD, Anastasia I. Kuznetsova MD, Tatyana L. Nekhaeva MD, PhD, Anna B. Danilova PhD, Irina A. Baldueva MD, PhD, Vladimir N. Anisimov MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2019-03-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735419833778

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https://doi.org/10.1177/1534735419833778

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