NAPE-PLD deletion in stress-TRAPed neurons results in an anxiogenic phenotype

Abstract Anandamide (AEA) is an endogenous ligand of the cannabinoid CB1 and CB2 receptors, being a component of the endocannabinoid signaling system, which supports the maintenance or regaining of neural homeostasis upon internal and external challenges. AEA is thought to play a protective role aga...

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Bibliographic Details
Main Authors: Margaryta Tevosian, Hristo Todorov, Ermelinda Lomazzo, Laura Bindila, Natsuo Ueda, Davide Bassetti, Davide Warm, Sergei Kirischuk, Heiko J. Luhmann, Susanne Gerber, Beat Lutz
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02448-9