Design, Synthesis, and Biological Evaluation of Benzylamino-Methanone Based Cholesteryl Ester Transfer Protein Inhibitors

Design, Synthesis, and Biological Evaluation of Benzylamino-Methanone Based Cholesteryl Ester Transfer Protein Inhibitors

Cholesteryl ester transfer protein (CETP) is a glycoprotein involved in transporting lipoprotein particles and neutral lipids between high-density lipoprotein (HDL) and low density lipoproteins (LDL) and therefore its a proper target for treating dyslipidemia and related disorders. Guided by our pre...

Full description

Bibliographic Details
Main Authors: Ghadeer Albadawi, Areej Melhem, Reema Abu Khalaf, Ghassan Abu Sheikha
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Molecules
Subjects:
CETP inhibitors
high-density lipoprotein
pharmacophore modeling
quantitative structure-activity relationship
benzylamino-methanones
Online Access:http://www.mdpi.com/1420-3049/15/8/5721/

Internet

http://www.mdpi.com/1420-3049/15/8/5721/

Similar Items