Sex- and age-specific reference intervals for diagnostic ratios reflecting relative activity of steroidogenic enzymes and pathways in adults.

Sex- and age-specific reference intervals for diagnostic ratios reflecting relative activity of steroidogenic enzymes and pathways in adults.

<h4>Objective</h4>Diagnostic ratios calculated from urinary steroid hormone metabolites are used as a measure for the relative activity of steroidogenic enzymes or pathways in the clinical investigation of steroid metabolism disorders. However, population-based sex- and age-specific refe...

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Bibliographic Details
Main Authors: Valentin Rousson, Daniel Ackermann, Belen Ponte, Menno Pruijm, Idris Guessous, Claudia H d'Uscio, Georg Ehret, Geneviève Escher, Antoinette Pechère-Bertschi, Michael Groessl, Pierre-Yves Martin, Michel Burnier, Bernhard Dick, Murielle Bochud, Bruno Vogt, Nasser A Dhayat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253975

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https://doi.org/10.1371/journal.pone.0253975

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